BDBM233727 US9353066, 3.25

SMILES COc1cccc(COc2ccc(cc2C(O)=O)-c2cc(C)cc(Nc3nccc(n3)C(F)(F)F)c2)c1

InChI Key InChIKey=KHZOXDSEWZLDKJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 233727   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM233727(US9353066, 3.25)
Affinity DataIC50:  17.4nMpH: 7.5 T: 25°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent