BDBM234387 10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b-azaindeno[2,1-a]indene-5,5-Dioxide (8a)

SMILES CN(C)CCOc1c2-c3ccccc3S(=O)(=O)n2c2ccccc12

InChI Key InChIKey=PWFDILKXFQTPQW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 234387   

TargetCytochrome P450 2D6(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 234387BDBM234387(10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b-azainden...)
Affinity DataIC50: 7.65E+3nMAssay Description:The cytochrome P450 inhibitory potential was determined using isoform-selective assays and heterologously expressed human CYP2D6 and CYP3A4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Suven Life Sciences

LigandChemical structure of BindingDB Monomer ID 234387BDBM234387(10-(2-N,N-Dimethylaminoethoxy)-5-Thia-4-b-azainden...)
Affinity DataIC50: 4.50E+4nMAssay Description:The cytochrome P450 inhibitory potential was determined using isoform-selective assays and heterologously expressed human CYP2D6 and CYP3A4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed