BDBM234457 US10004738, 10::US9353084, 10

SMILES Cc1csc(n1)C(=O)Nc1ccc(F)c(c1)[C@@]1(C)N=C(N)[C@@](C)(F)CC1(F)F

InChI Key InChIKey=JOQPMLZUFXKUND-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 234457   

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM234457(US9353084, 10 | US10004738, 10)
Affinity DataKi:  44nMpH: 4.5Assay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM234457(US9353084, 10 | US10004738, 10)
Affinity DataKi:  44nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent