BDBM234468 US10004738, 21::US9353084, 21

SMILES Cc1noc(n1)C(=O)Nc1ccc(F)c(c1)[C@@]1(C)N=C(N)[C@@](C)(F)CC1(F)F

InChI Key InChIKey=SUTNBTCNHDOKDD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 234468   

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM234468(US9353084, 21 | US10004738, 21)
Affinity DataKi:  58nMAssay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM234468(US9353084, 21 | US10004738, 21)
Affinity DataKi:  58nMpH: 4.5Assay Description:The binding assay was performed as SPA-based assay using a biotinylated form of human BACE1 recombinantly expressed and subsequently purified from Fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
US Patent