BDBM234967 4-(2-((4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)-n-(cyanomethyl)benzamide::US9556148, 38

SMILES O=C(NCC#N)c1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCC(CC2)N2C3CCC2COC3)n1

InChI Key InChIKey=SZPCGJVNXSNUIH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 234967   

TargetTyrosine-protein kinase JAK1(Human)
Cadila Healthcare

US Patent
LigandPNGBDBM234967(4-(2-((4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)p...)
Affinity DataIC50: 1.5nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Cadila Healthcare

US Patent
LigandPNGBDBM234967(4-(2-((4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)p...)
Affinity DataIC50: 4.30nMT: 2°CAssay Description:NCEs were screened using in vitro JAK (1, 2 and 3) kinase assay on ADP Glo platform (Promega). Fixed amount of recombinant purified human JAK (25 ng ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
US Patent