BDBM23527 2-{3-[3-(4-hydroxyphenyl)-1,2,4-oxadiazol-5-yl]propanamido}benzoic acid::Biaryl Anthranilide Analogue, 2i

SMILES OC(=O)c1ccccc1NC(=O)CCc1nc(no1)-c1ccc(O)cc1

InChI Key InChIKey=GRGWIIOJSGTREV-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 23527   

TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM23527(2-{3-[3-(4-hydroxyphenyl)-1,2,4-oxadiazol-5-yl]pro...)
Affinity DataIC50:  10nM EC50:  120nMpH: 7.4 T: 23°CAssay Description:Membranes were incubated in binding buffer with [5, 6-3H]-niacin in the presence of test compound. After 4 hours at room temperature, reactions were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM23527(2-{3-[3-(4-hydroxyphenyl)-1,2,4-oxadiazol-5-yl]pro...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human recombinant GPR109A receptor expressed in CHO-K1 cells after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

LigandPNGBDBM23527(2-{3-[3-(4-hydroxyphenyl)-1,2,4-oxadiazol-5-yl]pro...)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]nicotinic acid from human GPR109A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed