BDBM235782 US9359372, DC037035

SMILES COc1ccc(OC)c2CN3CCc4cc(O)c(O)cc4[C@@H]3Cc12

InChI Key InChIKey=QNEFEUWSOPMZJT-HNNXBMFYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235782   

TargetD(1A) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM235782(US9359372, DC037035)
Affinity DataKi:  6.72nM ΔG°:  -11.3kcal/molepH: 7.4 T: 30°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetD(1A) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM235782(US9359372, DC037035)
Affinity DataKi:  6.72nM ΔG°:  -11.3kcal/mole IC50:  13.3nMT: 30°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent