BDBM235878 US9364482, 53
SMILES CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2nc(COC)n(Cc3ccc(F)cc3)c(=O)c2c1)-c1ccc(F)cc1
InChI Key InChIKey=JEXBFVYJJWHBRA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 235878
Affinity DataIC50: 2.57nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
Affinity DataIC50: 2.45nMAssay Description:Stable neomycin phosphotransferase encoding replicons-harboring cell lines were used, so all cell lines were maintained under G418 selection prior to...More data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataEC50: 2.10nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 1a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataEC50: 2.40nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 1b by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataEC50: 19nMAssay Description:Non-nucleoside inhibition of NS5B polymerase S365A mutant in HCV genotype 1a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataEC50: 3.70nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 2b by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataEC50: 0.800nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 3a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataEC50: 0.900nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 4a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataEC50: 4.10nMAssay Description:Non-nucleoside inhibition of NS5B polymerase C316Y mutant in HCV genotype 1a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataEC50: 8.20nMAssay Description:Non-nucleoside inhibition of NS5B polymerase in HCV genotype 2a by Taqman probe based RT-PCR analysisMore data for this Ligand-Target Pair