BDBM236620 US9388136, Table 1, Compound 12:Cyclopentyl N-(5-{4-[6- amino-5-(2,4- difluorobenzoyl)- 2-oxopyridin- 1(2H)-yl]-3,5 - difluorophenoxy} pentyl)-L- leucinate

SMILES CC(C)C[C@H](NCCCCCOc1cc(F)c(c(F)c1)-n1c(N)c(ccc1=O)C(=O)c1ccc(F)cc1F)C(=O)OC1CCCC1

InChI Key InChIKey=RFLRUVLHHXEVTD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 236620   

TargetMitogen-activated protein kinase 14(Human)
Chroma Therapeutics

US Patent
LigandPNGBDBM236620(US9388136, Table 1, Compound 12:Cyclopentyl N-(5-{...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Chroma Therapeutics

US Patent
LigandPNGBDBM236620(US9388136, Table 1, Compound 12:Cyclopentyl N-(5-{...)
Affinity DataIC50: 81nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent