BDBM236621 US9388136, Table 1, Compound 13:Ethyl N-(3- {4-[6-amino- 5-(4-fluoro- benzoyl)-2- oxopyridin- 1(2H)-yl]-3,5- difluorophenoxy} propyl)-L- leucinate

SMILES CCOC(=O)[C@H](CC(C)C)NCCCOc1cc(F)c(c(F)c1)-n1c(N)c(ccc1=O)C(=O)c1ccc(F)cc1

InChI Key InChIKey=VWDDGZZBSAFMND-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 236621   

TargetMitogen-activated protein kinase 14(Human)
Chroma Therapeutics

US Patent
LigandPNGBDBM236621(US9388136, Table 1, Compound 13:Ethyl N-(3- {4-[6-...)
Affinity DataIC50: 28nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent