BDBM236630 US9388136, Table 1, Compound 22:tert-butyl (2S)- [(2-{4-[6-amino- 5-(2,4-difluoro- benzoyl)-2- oxopyridin- 1(2H)-yl]-3,5- difluorophenyl} ethyl)amino] (phenyl)acetate

SMILES CC(C)(C)OC(=O)[C@@H](NCCc1cc(F)c(c(F)c1)-n1c(N)c(ccc1=O)C(=O)c1ccc(F)cc1F)c1ccccc1

InChI Key InChIKey=NGDOHZFWCGDYCL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 236630   

TargetMitogen-activated protein kinase 14(Human)
Chroma Therapeutics

US Patent
LigandPNGBDBM236630(US9388136, Table 1, Compound 22:tert-butyl (2S)- [...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 14(Human)
Chroma Therapeutics

US Patent
LigandPNGBDBM236630(US9388136, Table 1, Compound 22:tert-butyl (2S)- [...)
Affinity DataIC50: 44nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent