BDBM236652 US9388139, 21

SMILES CC(C)(C)C1=NN(C(C1)c1ccc(Cl)cc1)c1ccc(cc1)C(O)=O

InChI Key InChIKey=NUCGZDHKOKKLHY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 236652   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
German University

US Patent
LigandPNGBDBM236652(US9388139, 21)
Affinity DataIC50: 8.70E+3nMAssay Description:PDE activity was measured using the IMAP fluorescence polarization assay (Molecular Devices) in which binding of hydrolyzed cyclic nucleotide substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetProstaglandin G/H synthase 1(Human)
German University

US Patent
LigandPNGBDBM236652(US9388139, 21)
Affinity DataIC50: 1.00E+5nMAssay Description:The activities of COX-1 and COX-2 were measured after the addition of arachidonic acid and incubation at 25° C. for 5 min by absorbance at 590 nm as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetProstaglandin G/H synthase 2(Human)
German University

US Patent
LigandPNGBDBM236652(US9388139, 21)
Affinity DataIC50: 1.00E+5nMAssay Description:The activities of COX-1 and COX-2 were measured after the addition of arachidonic acid and incubation at 25° C. for 5 min by absorbance at 590 nm as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent