BDBM236882 US9388171, I-24
SMILES COc1ccc(cc1F)[C@H](NC(=O)c1ccc2cnc(N[C@@H](C)CO)cc2n1)c1cnn(C)c1
InChI Key InChIKey=WRSGIHWQWREBIP-PSLXWICFSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 236882
Affinity DataIC50: 37.8nMT: 37°CAssay Description:HepG2 cells were obtained from ATCC and grown in DMEM supplemented with 10% fetal bovine serum. Cells were plated in 96-well plates at 35,000 cells/w...More data for this Ligand-Target Pair
Affinity DataIC50: 1.15nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair