BDBM237660 US9394263, 73

SMILES CN[C@@H](C)C(=O)N[C@@H]1C(=O)N(Cc2cccc3n(c(cc23)C#N)-c2ccccc2C#N)c2ccccc2OC11CCOCC1

InChI Key InChIKey=NOHIOXNNRUHMPA-WKRVVKTRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 237660   

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM237660(US9394263, 73)
Affinity DataIC50:  2.86E+3nMpH: 7.5 T: 25°CAssay Description:Ten nanomolar of 6x Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM237660(US9394263, 73)
Affinity DataIC50:  32nMpH: 7.5 T: 25°CAssay Description:Ten nanomolar of 6x Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent