BDBM238706 US9394297, 370
SMILES Cc1nc2ccc(F)c(-c3cc4c(CCNC4=O)[nH]3)c2nc1NC(C)(C)CO
InChI Key InChIKey=QYKGYRLGHZIFTF-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 238706
Affinity DataIC50: 0.992nMpH: 7.0 T: 22°CAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Affinity DataIC50: 0.272nMpH: 7.0 T: 22°CAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
Affinity DataIC50: 143nMAssay Description:Inhibition of pan Pim in human KMS-12-BM cells assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 residue after 110 m...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of full length recombinant Pim-2 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of full length recombinant Pim-1 (unknown origin) assessed as reduction in phosphorylation of biotinylated-BAD peptide at Serine 112 resid...More data for this Ligand-Target Pair