BDBM239080 US9416126, A1

SMILES Cn1cc(cn1)-c1ccc2[nH]nc(-c3cc(ncn3)N3CCOCC3)c2c1

InChI Key InChIKey=PLVINOPYHPWDGC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 239080   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [970-2527](Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM239080(US9416126, A1)
Affinity DataIC50:  41nMpH: 8.5 T: 2°CAssay Description:a) 400 nl of a 1:2.15 serial dilution of test compound(98 μM top assay concentration) is spotted via Labcyte Echo to certain wells in a 384 well...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [970-2527](Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM239080(US9416126, A1)
Affinity DataIC50:  2.31nMpH: 8.5 T: 2°CAssay Description:a) 400 nl of a 1:2.15 serial dilution of test compound(98 μM top assay concentration) is spotted via Labcyte Echo to certain wells in a 384 well b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent