BDBM239172 Thiazolidin-based CA inhibitor, 2

SMILES Cc1ccsc1C1SCC(=O)N1c1cccc(C)n1

InChI Key InChIKey=UHPAMAYDFAGJAF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 239172   

TargetCarbonic anhydrase 2(Human)
Ondokuz Mayis University

LigandPNGBDBM239172(Thiazolidin-based CA inhibitor, 2)
Affinity DataKi:  2.48E+3nM ΔG°:  -7.64kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ondokuz Mayis University

LigandPNGBDBM239172(Thiazolidin-based CA inhibitor, 2)
Affinity DataKi:  4.75E+4nM ΔG°:  -5.89kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2017
Entry Details Article
PubMed