BDBM239778 Roche-Dataset for PDE10A, Compound 97::US9394311, 61

SMILES COc1ccc(Cn2nc(nc2CCc2nc3c(Cl)cc(Cl)c(C)n3n2)N2CCCC2)cc1

InChI Key InChIKey=WXBGRWPXCUUDSN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 239778   

LigandPNGBDBM239778(Roche-Dataset for PDE10A, Compound 97 | US9394311,...)
Affinity DataIC50:  0.640nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM239778(Roche-Dataset for PDE10A, Compound 97 | US9394311,...)
Affinity DataIC50:  0.720nMT: 25°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent