BDBM239778 Roche-Dataset for PDE10A, Compound 97::US9394311, 61

SMILES COc1ccc(Cn2nc(nc2CCc2nc3c(Cl)cc(Cl)c(C)n3n2)N2CCCC2)cc1

InChI Key InChIKey=WXBGRWPXCUUDSN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 239778   

LigandPNGBDBM239778(US9394311, 61 | Roche-Dataset for PDE10A, Compound...)
Affinity DataIC50: 0.640nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details Article
PubMed
LigandPNGBDBM239778(US9394311, 61 | Roche-Dataset for PDE10A, Compound...)
Affinity DataIC50: 0.720nMT: 2°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2017
Entry Details
US Patent