BDBM239851 Roche-Dataset for PDE10A, Compound 127::US9394311, 132

SMILES Cc1c(Cl)cc(c2nc(CCc3nc(nn3C3CC3)N3CCCC3)nn12)C(F)(F)F

InChI Key InChIKey=INSBMSXKAQMIQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 239851   

LigandPNGBDBM239851(Roche-Dataset for PDE10A, Compound 127 | US9394311...)
Affinity DataIC50:  0.720nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

LigandPNGBDBM239851(Roche-Dataset for PDE10A, Compound 127 | US9394311...)
Affinity DataIC50:  0.720nMT: 25°CAssay Description:The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent