BDBM240596 US9409882, 1

SMILES COc1ccc(c(Cl)c1)S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)c1ccc(Cl)cn1)C(=O)NC1(CC1)C#N

InChI Key InChIKey=BABQKRHMVVUNBI-MJGOQNOKSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 240596   

TargetCathepsin S(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM240596(US9409882, 1)
Affinity DataIC50:  0.606nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM240596(US9409882, 1)
Affinity DataIC50:  410nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCathepsin K(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM240596(US9409882, 1)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of Cathepsin K (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed

TargetCathepsin S(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM240596(US9409882, 1)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of Cathepsin S (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM240596(US9409882, 1)
Affinity DataIC50:  410nMAssay Description:Inhibition of human Cathepsin LMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed