BDBM240597 US9409882, 2

SMILES Clc1ccc(nc1)C1(CC1)C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)S(=O)(=O)c1ccccc1Cl

InChI Key InChIKey=AJGQRLLAZUYHKK-AEFFLSMTSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 240597   

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM240597(US9409882, 2)
Affinity DataIC50:  340nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetCathepsin S(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM240597(US9409882, 2)
Affinity DataIC50:  0.492nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent