BDBM240634 US9409882, 39

SMILES Cn1cc(cn1)-c1ccc(c(Cl)c1)S(=O)(=O)[C@@H]1C[C@H](N(C1)C(=O)C1(CC1)c1ncc(cc1F)C(F)(F)F)C(=O)NC1(CC1)C#N

InChI Key InChIKey=ACTMEZFPDCIVQO-KNQAVFIVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 240634   

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM240634(US9409882, 39)
Affinity DataIC50:  43.6nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetCathepsin S(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM240634(US9409882, 39)
Affinity DataIC50:  0.696nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent