BDBM240718 US9422243, 18

SMILES NCCOc1c([nH]c(=O)c2cc(F)ccc12)-c1ccc(N2CCCC2)c(Br)c1

InChI Key InChIKey=AUSDJKWCUGOMRT-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 240718   

TargetPoly [ADP-ribose] polymerase 1(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240718(US9422243, 18)
Affinity DataKd:  60nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetPoly [ADP-ribose] polymerase 1(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240718(US9422243, 18)
Affinity DataIC50:  130nMT: 37°CAssay Description:Studies were performed as follows: 6000 cells/well were seeded in 96 well plates (Perkin Elmer) in MEM/10% FCS and incubated for 24 hs at 37° C.,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM240718(US9422243, 18)
Affinity DataKd:  20nMAssay Description:The identification of compounds capable of binding several PARP proteins is carried out through a screening method including the steps of a) provi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent