BDBM241472 US9409908, 104::US9951071, Example 104

SMILES COC(=O)Nc1ccc2c(c1)NC(=O)[C@H](C)CCC[C@H](N1CCC(c3c(C#N)ccc(C)c3F)=CC1=O)c1cc-2ccn1

InChI Key InChIKey=BIQNYXOWWCZXBD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 241472   

TargetCoagulation factor IX(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 241472BDBM241472(US9409908, 104 | US9951071, Example 104)
Affinity DataKi:  0.0900nMpH: 7.4Assay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 241472BDBM241472(US9409908, 104 | US9951071, Example 104)
Affinity DataKi:  0.0900nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
US Patent