BDBM241619 US9409915, 11::US9718820, Compound 11
SMILES COc1nc(cc2nc([nH]c12)-c1c(Cl)c(nn1C)C(C)(C)C)-c1ccccc1Cl
InChI Key InChIKey=BWNRDOOTXFSNPN-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 241619
Affinity DataIC50: 3.5nMT: 37°CAssay Description:HEK293 cells stably expressing canine TRPM8 were routinely grown as monolayers in Dulbecco's minimum essential medium supplemented with 10% FBS, 2 mM...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Human)
Instituto De Qu£Mica M£Dica
Curated by ChEMBL
Instituto De Qu£Mica M£Dica
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at human TRMP8 incubated for 24 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMT: 25°CAssay Description:HEK293 cells stably expressing canine TRPM8 were routinely grown as monolayers in Dulbecco's minimum essential medium supplemented with 10% FBS, ...More data for this Ligand-Target Pair