BDBM242229 US9416129, 7
SMILES CN1C(=N)N[C@@](C)(CS1(=O)=O)c1sc(cc1F)-c1cccc(c1)-c1ncco1
InChI Key InChIKey=RDFXNEIPFIKQQK-SFHVURJKSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 242229
Affinity DataKi: 0.730nM ΔG°: -12.7kcal/molepH: 5.0 T: 30°CAssay Description:Inhibitor compounds, prepared at 3× the desired final concentration in 1×BACE assay buffer (20 mM sodium acetate pH 5.0, 10% glycerol, 0....More data for this Ligand-Target Pair
Affinity DataKi: 8.70nM ΔG°: -11.2kcal/molepH: 5.0 T: 30°CAssay Description:Varying concentrations of inhibitors at 3× the final desired concentration in a volume of 10 μl are preincubated with purified human BACE1 c...More data for this Ligand-Target Pair