BDBM24224 1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}piperidin-4-ol::Benzthiazole compound, 27e

SMILES OC1CCN(CCc2ccc(Oc3nc4ccccc4s3)cc2)CC1

InChI Key InChIKey=HHJAPVOVRQGCFN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24224   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM24224(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}pip...)
Affinity DataIC50:  3.00E+3nMpH: 7.4 T: 2°CAssay Description:Compounds were assessed for their ability to displace [3H]astemizole using membranes from HEK-293 cells expressing the hERG K+ channel.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM24224(1-{2-[4-(1,3-benzothiazol-2-yloxy)phenyl]ethyl}pip...)
Affinity DataIC50:  8nMpH: 7.4 T: 2°CAssay Description:Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed