BDBM243341 US10053454, Example 85::US10196387, Example 85

SMILES Cc1noc(C)c1-c1cc(-c2nnc[nH]2)c2c(c1)c1ccc(C(=O)N3C[C@@H](C)O[C@@H](C)C3)cc1n2CC1CC1

InChI Key InChIKey=ZTQQZCJPOWEODU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 243341   

TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 243341BDBM243341(US10053454, Example 85 | US10196387, Example 85)
Affinity DataIC50: 500nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Bristol Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 243341BDBM243341(US10053454, Example 85 | US10196387, Example 85)
Affinity DataIC50: 500nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
US Patent