BDBM2437 US8507533, 157

SMILES CC1(C)CC(C1)C(Nc1cnc(nc1)-n1cc(cn1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O

InChI Key InChIKey=YDXHIJKYXAXQTE-UHFFFAOYSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2437   

TargetPro-glucagon(Human)
Pfizer

US Patent

LigandBDBM2437(US8507533, 157)Copy SMILESCopy InChI

Affinity DataKi:  5.55nMAssay Description:The Glucagon SPA assay is used to determine the ability of test compounds to block the binding of glucagon-cex to the glucagon receptors.More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent

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TargetGlucagon receptor(Human)
Pfizer

Curated by ChEMBL

LigandBDBM2437(US8507533, 157)Copy SMILESCopy InChI

Affinity DataKi:  5.60nMAssay Description:Displacement of [125I]-glucagon from human glucagon receptor expressed in Chem-1 cell membranes after 6 to 10 hrs by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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