BDBM244246 US9546173, cmpd 166::n-(2-((dimethylamino)methyl)benzyl)-5,5-dimethyl-2-(phenylamino)-5h-pyrrolo[3,4-d]pyrimidine-6(7h)-carboxamide

SMILES CN(C)Cc1ccccc1CNC(=O)N1Cc2nc(Nc3ccccc3)ncc2C1(C)C

InChI Key InChIKey=UGOGDZQMZZVPGL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 244246   

TargetRibosomal protein S6 kinase alpha-3(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 244246BDBM244246(n-(2-((dimethylamino)methyl)benzyl)-5,5-dimethyl-2...)
Affinity DataIC50: 1.63E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details
US Patent

TargetMitogen-activated protein kinase 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 244246BDBM244246(n-(2-((dimethylamino)methyl)benzyl)-5,5-dimethyl-2...)
Affinity DataIC50: 4.48E+4nMpH: 7.5Assay Description:Compound potency against activated ERK2 was determined using a kinase assay that measures ERK2-catalyzed phosphorylation of biotinylated ERKtide pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details
US Patent