BDBM24485 3-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-1-(2-phenylacetyl)thiourea::CHEMBL404881::Inhibitor III
SMILES COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)c2cc1OC
InChI Key InChIKey=NDECJXFIPXCRJU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 24485
Affinity DataKi: 1nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of recombinant c-met-mediated gastrin phosphorylation by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of GST-tagged c-Met expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of c-Met (unknown origin) using poly Glu:Tyr (4:1) as substrate after 60 mins by liquid scintillation counting analysis in presence of [ga...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of kinase activity was measured in a DELFIA assay (Perkin-Elmer). The substrate poly (Glu4, Tyr) was immobilized onto black high-binding p...More data for this Ligand-Target Pair
Affinity DataIC50: 121nMpH: 7.5 T: 30°CAssay Description:Inhibition of kinase activity was measured in a DELFIA assay (Perkin-Elmer). The substrate poly (Glu4, Tyr) was immobilized onto black high-binding p...More data for this Ligand-Target Pair
Affinity DataIC50: 121nMAssay Description:Inhibition of c-Met phosphorylationMore data for this Ligand-Target Pair