BDBM245167 US9428460, 23

SMILES N#Cc1cccc2c(O[C@H]3CC[C@H](NC(=O)c4cccc(F)c4)CC3)ccnc12

InChI Key InChIKey=YPARZKBHGSVSFI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 245167   

TargetAndrogen receptor [E709Y](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 245167BDBM245167(US9428460, 23)
Affinity DataIC50: 9nMT: 2°CAssay Description:PC-3 cells (Kaighn et al., Invest. Urol. 17: 16-23, 1979) were plated out at a density of 10000 cells per well of a 96-well cell culture plate in RMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetAndrogen receptor [W742C](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 245167BDBM245167(US9428460, 23)
Affinity DataIC50: 30nMT: 2°CAssay Description:PC-3 cells (Kaighn et al., Invest. Urol. 17: 16-23, 1979) were plated out at a density of 10000 cells per well of a 96-well cell culture plate in RMP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetAndrogen receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 245167BDBM245167(US9428460, 23)
Affinity DataIC50: 52nMT: 2°CAssay Description:For determining the androgen receptor-dependent transcription, a cellular assay system was used, consisting of PC-3 cells (Kaighn et al., Invest. Uro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent