BDBM245921 US9433609, 11
SMILES CO[C@@H](C)[C@@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2nc([nH]c2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C
InChI Key InChIKey=NUJYJEUAUQASEY-SJNLCZQDSA-N
Data 10 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 245921
TargetGenome polyprotein [1657-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataEC50: 0.00600nMAssay Description:The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...More data for this Ligand-Target Pair
TargetGenome polyprotein [1657-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataEC50: 0.0120nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
TargetGenome polyprotein [1657-3011](Hepatitis C virus genotype 1a (isolate H77) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataEC50: 0.0480nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419,L2000T](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataEC50: 0.117nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419,Y2165C](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataEC50: <0.0130nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419,L2003F](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataEC50: 0.0210nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419,L2003M](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataEC50: 0.0870nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419,L2003V](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataEC50: 0.141nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419,Y2165H](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataEC50: 0.167nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair
TargetGenome polyprotein [1973-2419,R2002H](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataEC50: 0.0500nMAssay Description:In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...More data for this Ligand-Target Pair