BDBM246553 2-Chloro-4-{[2-(hydroxymethyl)-1H-benzimidazol-1-yl]acetyl}benzenesulfonamide (2c)

SMILES NS(=O)(=O)c1ccc(cc1Cl)C(=O)Cn1c(CO)nc2ccccc12

InChI Key InChIKey=XLIOJXAHVPIGDE-UHFFFAOYSA-N

Data  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 246553   

TargetCarbonic anhydrase 1(Human)
Vilnius University

LigandPNGBDBM246553(2-Chloro-4-{[2-(hydroxymethyl)-1H-benzimidazol-1-y...)
Affinity DataKd:  10nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 2(Human)
Vilnius University

LigandPNGBDBM246553(2-Chloro-4-{[2-(hydroxymethyl)-1H-benzimidazol-1-y...)
Affinity DataKd:  14.3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 13(Human)
Vilnius University

LigandPNGBDBM246553(2-Chloro-4-{[2-(hydroxymethyl)-1H-benzimidazol-1-y...)
Affinity DataKd:  66.7nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 12(Human)
Vilnius University

LigandPNGBDBM246553(2-Chloro-4-{[2-(hydroxymethyl)-1H-benzimidazol-1-y...)
Affinity DataKd:  1.00E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCarbonic anhydrase 7(Human)
Vilnius University

LigandPNGBDBM246553(2-Chloro-4-{[2-(hydroxymethyl)-1H-benzimidazol-1-y...)
Affinity DataKd:  5nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed