BDBM246948 (5S)-3-[2-Chloro-3-(trifluoromethyl)phenyl]-5-methyl-8-pyrimidin-2-yl-5,6-dihydrobis[1,2,4]triazolo[4,3-a:3′,4′-c]pyrazine::US10053463, 105
SMILES C[C@H]1Cn2c(nnc2-c2ncccn2)-c2nnc(-c3cccc(c3Cl)C(F)(F)F)n12
InChI Key InChIKey=ASQFMFPWWORJLB-VIFPVBQESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 246948
Affinity DataKi: 4nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according ...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:human or rat P2X7-1321N1 cells were collected and frozen @−80° C. On the day of the experiment, cell membrane preparations were made according ...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
Affinity DataIC50: 11.3nMpH: 7.4Assay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair