BDBM247002 ({4-[4-(2-{[(3R,3aR,6R,6aR)-6-Hydroxy-hexahydrofuro[3,2-b]furan-3-yl]oxy}-6-fluoro-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazo[4,5-b]pyridin-5-yl)phenyl]phenyl}-imino)dimethyl-λ6-sulfanone::US10053471, 13

SMILES CS(=N)(=O)c1ccc(c(F)c1)-c1ccc(cc1)-c1nc2[nH]c(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)nc2cc1Cl

InChI Key InChIKey=ZFFSLCDXVLHXDQ-UHFFFAOYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 247002   

Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Human)
Boehringer Ingelheim International

US Patent

LigandBDBM247002(({4-[4-(2-{[(3R,3aR,6R,6aR)-6-Hydroxy-hexahydrofur...)Copy SMILESCopy InChI

Affinity DataEC50:  71nMpH: 7.0 T: 2°CAssay Description:The test compounds were dissolved in 100% DMSO at a concentration of 10 mM and in a first step diluted in DMSO to a concentration of 5 mM, followed b...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/30/2018
Entry Details
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