BDBM247255 US9447029, 1-14

SMILES CN(C)C(=O)CNCC(F)(F)c1cccc(OCc2ccccc2)c1

InChI Key InChIKey=OWKULWIAAHYFTD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 247255   

TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Newron Pharmaceuticals

US Patent
LigandPNGBDBM247255(US9447029, 1-14)
Affinity DataKi:  500nMAssay Description:Cells and methods: Functional inhibition of the sodium currents is studied using whole cell patch clamp methods (Hamill O. P., Marty A., Neher E., Sa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Newron Pharmaceuticals

US Patent
LigandPNGBDBM247255(US9447029, 1-14)
Affinity DataIC50: 4.00E+4nMT: 2°CAssay Description:Test compound is dissolved in DMSO 500× the highest final concentration desired in the IC50 assay. 30 ml of deionized water is pre-warmed to 37...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
US Patent