BDBM247270 US9447029, 2-[2-(3-Pentyloxyphenyl)-ethylamino]-N,N-dimethyl-acetamide

SMILES CCCCCOc1cccc(CCNCC(=O)N(C)C)c1

InChI Key InChIKey=VRLSELRYHHSXAL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 247270   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Southampton

Curated by ChEMBL
LigandPNGBDBM247270(US9447029, 2-[2-(3-Pentyloxyphenyl)-ethylamino]-N,...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human ERG assessed as reduction in channel tail current by plate-based planar patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Newron Pharmaceuticals

US Patent
LigandPNGBDBM247270(US9447029, 2-[2-(3-Pentyloxyphenyl)-ethylamino]-N,...)
Affinity DataIC50: 3.50E+3nMT: 2°CAssay Description:Test compound is dissolved in DMSO 500× the highest final concentration desired in the IC50 assay. 30 ml of deionized water is pre-warmed to 37...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
US Patent