BDBM24771 5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-3-methyl-2-{[4-(trifluoromethyl)phenyl]amino}-3,4-dihydropyrimidin-4-one::pyrimidone, 56

SMILES COc1cc2nccc(Oc3ccc(cc3F)-c3cnc(Nc4ccc(cc4)C(F)(F)F)n(C)c3=O)c2cc1OC

InChI Key InChIKey=WKDSRSWTJRXFHC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24771   

LigandPNGBDBM24771(5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophe...)
Affinity DataKi:  136nM ΔG°:  -9.27kcal/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24771(5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophe...)
Affinity DataIC50:  136nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed