BDBM24772 2-[(4-fluorophenyl)amino]-5-[5-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quinolin-4-yl}oxy)pyridin-2-yl]-3-methyl-3,4-dihydropyrimidin-4-one::pyrimidone, 62

SMILES COc1cc2c(Oc3ccc(nc3)-c3cnc(Nc4ccc(F)cc4)n(C)c3=O)ccnc2cc1OCCCN1CCOCC1

InChI Key InChIKey=UVNDVSUMHWZESZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24772   

LigandPNGBDBM24772(2-[(4-fluorophenyl)amino]-5-[5-({6-methoxy-7-[3-(m...)
Affinity DataKi:  3.40nM ΔG°:  -11.4kcal/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM24772(2-[(4-fluorophenyl)amino]-5-[5-({6-methoxy-7-[3-(m...)
Affinity DataKi:  83nM ΔG°:  -9.56kcal/molepH: 7.5 T: 22°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed