BDBM24863 Pyridopyrimidine, 12h::methyl({4-[2-(methylsulfanyl)-6-phenylpyrido[2,3-d]pyrimidin-7-yl]phenyl}methyl)[2-(1H-pyrazol-4-yl)ethyl]amine

SMILES CSc1ncc2cc(-c3ccccc3)c(nc2n1)-c1ccc(CN(C)CCc2cn[nH]c2)cc1

InChI Key InChIKey=GQEPHZRQVGFQLK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24863   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

LigandPNGBDBM24863(methyl({4-[2-(methylsulfanyl)-6-phenylpyrido[2,3-d...)
Affinity DataIC50: 1.52E+3nMpH: 7.5 T: 2°CAssay Description:Purified recombinant human Akt kinase was monitored for kinase activity in the presence or absence of inhibitors in a 96-well format. Detection was d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2008
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

LigandPNGBDBM24863(methyl({4-[2-(methylsulfanyl)-6-phenylpyrido[2,3-d...)
Affinity DataIC50: 1.75E+4nMAssay Description:Purified recombinant human Akt kinase was monitored for kinase activity in the presence or absence of inhibitors in a 96-well format. Detection was d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2008
Entry Details Article
PubMed