BDBM24866 5-{2-[({4-[2-(methylsulfanyl)-6-phenylpyrido[2,3-d]pyrimidin-7-yl]phenyl}methyl)amino]ethyl}-1,3,4-thiadiazol-2-amine::Pyridopyrimidine, 12k

SMILES CSc1ncc2cc(-c3ccccc3)c(nc2n1)-c1ccc(CNCCc2nnc(N)s2)cc1

InChI Key InChIKey=ZFGVHTJRILVQEN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24866   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

LigandPNGBDBM24866(5-{2-[({4-[2-(methylsulfanyl)-6-phenylpyrido[2,3-d...)
Affinity DataIC50: 46nMpH: 7.5 T: 2°CAssay Description:Purified recombinant human Akt kinase was monitored for kinase activity in the presence or absence of inhibitors in a 96-well format. Detection was d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2008
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

LigandPNGBDBM24866(5-{2-[({4-[2-(methylsulfanyl)-6-phenylpyrido[2,3-d...)
Affinity DataIC50: 529nMAssay Description:Purified recombinant human Akt kinase was monitored for kinase activity in the presence or absence of inhibitors in a 96-well format. Detection was d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2008
Entry Details Article
PubMed