BDBM249138 US9453038, 16

SMILES CN1C(=O)CCC1c1cc2[nH]c(-c3ccc(CCC(=O)O)cn3)cc2cc1Oc1ccc(S(C)(=O)=O)cc1

InChI Key InChIKey=XYJYFORPIPUOLC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 249138   

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249138BDBM249138(US9453038, 16)
Affinity DataEC50:  51.5nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249138BDBM249138(US9453038, 16)
Affinity DataEC50:  111nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent