BDBM249274 US10017501, Compound 1020-4::US9458145, 1020-4

SMILES CSc1nc2c(S(=O)(=O)NC3CCCC3)cc(-c3c(C)noc3C)cc2[nH]1

InChI Key InChIKey=LWWBJYKHKNDJHR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 249274   

TargetBromodomain-containing protein 4 [368-440](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 249274BDBM249274(US9458145, 1020-4 | US10017501, Compound 1020-4)
Affinity DataIC50: 230nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [368-440](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 249274BDBM249274(US9458145, 1020-4 | US10017501, Compound 1020-4)
Affinity DataIC50: 230nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 249274BDBM249274(US9458145, 1020-4 | US10017501, Compound 1020-4)
Affinity DataIC50: 337nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 249274BDBM249274(US9458145, 1020-4 | US10017501, Compound 1020-4)
Affinity DataIC50: 337nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent