BDBM249304 US10017501, Compound 1020-148::US9458145, 1020-148

SMILES Cc1noc(C)c1-c1cc(S(=O)(=O)NC2CCCC2)c2nc(NCC(F)(F)F)[nH]c2c1

InChI Key InChIKey=HDARKJYJRLDMQA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 249304   

TargetBromodomain-containing protein 4 [368-440](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 249304BDBM249304(US9458145, 1020-148 | US10017501, Compound 1020-14...)
Affinity DataIC50: 180nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [368-440](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 249304BDBM249304(US9458145, 1020-148 | US10017501, Compound 1020-14...)
Affinity DataIC50: 180nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 249304BDBM249304(US9458145, 1020-148 | US10017501, Compound 1020-14...)
Affinity DataIC50: 186nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetBromodomain-containing protein 4 [75-147](Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 249304BDBM249304(US9458145, 1020-148 | US10017501, Compound 1020-14...)
Affinity DataIC50: 186nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details
US Patent