BDBM249372 US9464081, 5

SMILES CO[C@H]1[C@@H](C(=O)NCC(F)=C(C)C)N(C(=O)Cn2nc(C(N)=O)c3ccncc32)C[C@@H]1F

InChI Key InChIKey=UJTMJIREXFSZKT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 249372   

TargetComplement factor D(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 249372BDBM249372(US9464081, 5)
Affinity DataIC50: 253nMpH: 7.5 T: 2°CAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent