BDBM249998 US10005782, Compound 124::US9447106, 124::US9556188, Compound 124

SMILES CN(C)C\C=C\C(=O)N1CCCc2[nH]c3c(C(N)=O)c(nn3c2C1)-c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=OSMWOWJTRFYNSD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 249998   

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM249998(US9447106, 124 | US9556188, Compound 124 | US10005...)
Affinity DataIC50: 0.620nMT: 2°CAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM249998(US9447106, 124 | US9556188, Compound 124 | US10005...)
Affinity DataIC50: 0.620nMAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM249998(US9447106, 124 | US9556188, Compound 124 | US10005...)
Affinity DataIC50: 0.620nMT: 2°CAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
US Patent