BDBM250085 US10005782, Compound 30a::US9447106, 30a (peak 1)

SMILES NC(=O)c1c2NC[C@@H]3CN(CC[C@H]3n2nc1-c1ccc(Oc2ccccc2)cc1)C(=O)C=C

InChI Key InChIKey=STKAJAXFRAFMLO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 250085   

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM250085(US9447106, 30a (peak 1) | US10005782, Compound 30a)
Affinity DataIC50: 0.660nMT: 2°CAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Beigene

US Patent
LigandPNGBDBM250085(US9447106, 30a (peak 1) | US10005782, Compound 30a)
Affinity DataIC50: 0.660nMAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2020
Entry Details
US Patent