BDBM250423 US9464044, 13

SMILES Cc1cccc(F)c1S(=O)(=O)N(C)CC1(C(=O)NC2C3CC4CC2CC(C(N)=O)(C4)C3)CC1

InChI Key InChIKey=XJHYIRPKXZRYMU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 250423   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Ahn-Gook Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 250423BDBM250423(US9464044, 13)
Affinity DataIC50: 2.80nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details
US Patent