BDBM250445 US9464044, 41

SMILES Cc1c(Cl)cccc1S(=O)(=O)NC1(C(=O)NC2C3CC4CC2CC(C(N)=O)(C4)C3)CC1

InChI Key InChIKey=XMKLDAOIBDQRAC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 250445   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Ahn-Gook Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 250445BDBM250445(US9464044, 41)
Affinity DataIC50: 10nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details
US Patent